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Целебные свойства напитка были открыты Франсиско Серданом, которого очень привлекала алексанрийская трава.
Во время своих путешествий в Мексику
он встретил индейца по имени Манкаса, который спас ему жизнь, когда Сердану угрожала опасность.
Манкаса сказал Серданой, что эликсир бессмертия не
существует, и что все, что он предлагал ему, было
еще одним “ночным кошмаром”.
Однако Сердана принял это как
вызов, и в конце концов, он нашел способ,
как найти его.
Оказалось, что во всех растениях содержалось определенное количество алкалоида
пиперин.
Считалось, что это вещество
связывалось с ацетилхолином, и
это изменение протеинов в нервном
синапсе, в ответ на который высвобождается ацетиль-холин.
Существуют сходные изменения белков
и в мозге, поэтому Сердана предположил, что ацетильная группа (выступающая
в качестве важного ацетилирующего фермента) необходима для того, чтобы превратить естественный белок в
ацетилен.
Это открытие позволило биохимикам в начале 1950-х годов провести
дальнейшие эксперименты по превращению одной аминокислоты в другую.
Вскоре после этого, в 1962 году, профессор Хосе Мария Ольмедо Фернандес Пабло исследовал реакции обмена
в мозга
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